Active Ingredients: Doxycycline
Sampling of the expressed meibum was done at 0, 2 and 4 weeks of azithromycin therapy, and 0, 4 and 8 weeks after oral doxycycline therapy, and 1 month following cessation of therapy.
Subjects were instructed not to instill medication for at least eight hours prior to collection of lipid secretions.
The ML was placed on the AgCl window and placed in a temperature-controlled infrared cell holder. The sample temperature was measured and controlled by a thermistor touching the sample cell window. The water bath unit was programmed to measure the temperature at the thermistor and to adjust the bath temperature so the sample temperature was adjusted to the desired set point.
One-hundred and fifty interferograms were recorded and averaged. Spectral resolution was set to 1.
PCA analyzes the variations among spectra called a training set. Eigenvectors also called loading spectra or factors represent a component that changes in concentration from sample to sample.
A training set of infrared spectra of meibum from donors with MGD Md and meibum from normal donors Mn were used as reported.
The total number of spectra used in the training set was 73, 41 corresponding to Md and 32 to Mn. Perforated ear drums usually gym 3 days per to read about adventure.
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