Active Ingredients: Doxycycline
Supplementation with protein, appropriate fluid and electrolyte management, antibiotic treatment of bacteria responsible for diarrhea Clostridium difficile, and surgical evaluation if it is clinically indicated should be undertaken.
Discoloration of teeth Children up to the age of 8 years are at an increased risk when using this medicine. Such patients have an increased risk of developing permanent discoloration of teeth yellow-grey-brown and tooth defect enamel hypoplasia.
These side-effects occur more commonly during long-term use of the medicine.
The use of this drug should not be prescribed for children up to 8 years except for a rare and severe bacterial illness anthrax until and unless any other effective treatment is not available. Syphilis testing If syphilis along with existing bacterial disease is suspected during the treatment with this medicine, then follow dark-field examinations laboratory test before starting the treatment.
Another method of laboratory testing blood serology should be done repeatedly for at least four months. Monitoring of laboratory tests while long-term therapy with Tabocine In patients for whom long-term therapy is prescribed, laboratory examination of organ systems, including blood, kidney, and liver should be performed at regular time intervals.
Ulceration and irritation in food pipe oesophageal irritation and ulceration Such patients are at an increased risk to develop ulcers and irritation in food pipe when using this medicine. These patients should take adequate fluids so as to avoid the risk of developing ulcers and irritation of food pipe.
Patients with history of fungal infection in the mouth oral candidosis Such patients are at an increased risk of having a fungal infection in the vagina when using this medicine.
Take necessary precautions while using this medicine in patients with the history of fungal infection in the mouth. Abnormal functioning of the liver Tabocine should be taken cautiously in patients with abnormal functioning of the liver.
Interactions with Tabocine When two or more medicines are taken together, it can change how the medicines work and increase the risk of side-effects. In medical terms, this is called as a Drug Interaction.
Tabocine capsule interacts with antacids, which are used to treat stomach acidity. It is advisable not to give Tabocine with beta-lactam antibiotics penicillins. Tetracyclines such as Tabocine have been shown to depress the blood clotting time blood prothrombin activity.
When Tabocine is taken in combination with anticoagulants, coagulation parameters, including International Normalized Ratio INR, should be monitored properly.
The possibility of an increased risk of bleeding events should be known to the patient. Special instructions need to be followed while taking this medicine along with oral contraceptives, which are used for birth control preventive measures. Didanosine should, therefore, be used at least 2 hours after intake of Tabocine.
Tabocine capsule interacts with rifampicin, which is used to treat several types of bacterial infections such as tuberculosis.
Only few cases have been reported worldwide. We here report a case of a young man, presenting with acute onset of fever, left hypochondial pain, and vomiting.
Do. Shukla, and M. Foti et al.